BCG as a Case Study for Precision Vaccine Development: Lessons From Vaccine Heterogeneity, Trained Immunity, and Immune Ontogeny

Vaccines have been traditionally developed with the presumption that they exert identical immunogenicity regardless of target population and that they provide protection solely against their target pathogen. However, it is increasingly appreciated that vaccines can have off-target effects and that v...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Angelidou, Asimenia, Diray-Arce, Joann, Conti, Maria Giulia, Smolen, Kinga K., van Haren, Simon Daniël, Dowling, David J., Husson, Robert N., Levy, Ofer
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078104/
https://ncbi.nlm.nih.gov/pubmed/32218774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00332
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