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Synthetic and genomic regulatory elements reveal aspects of cis-regulatory grammar in mouse embryonic stem cells
In embryonic stem cells (ESCs), a core transcription factor (TF) network establishes the gene expression program necessary for pluripotency. To address how interactions between four key TFs contribute to cis-regulation in mouse ESCs, we assayed two massively parallel reporter assay (MPRA) libraries...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7077988/ https://ncbi.nlm.nih.gov/pubmed/32043966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41279 |
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