Modifiers and Subtype-Specific Analyses in Whole-Genome Association Studies: A Likelihood Framework

OBJECTIVE: We propose new statistical methods for analyzing genetic case/control association data in which cases can be further classified into subtypes, for example, based on clinical features. The primary utility of our work is the ability to distinguish between subtype-specific and modifier effec...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Hum Hered
Hoofdauteurs: Lee, Phil H., Bergen, Sarah E., Perlis, Roy H., Sullivan, Patrick F., Sklar, Pamela, Smoller, Jordan W., Purcell, Shaun M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: S. Karger AG 2011
Onderwerpen:
Original Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077092/
https://ncbi.nlm.nih.gov/pubmed/21849790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000327158
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items