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Modifiers and Subtype-Specific Analyses in Whole-Genome Association Studies: A Likelihood Framework
OBJECTIVE: We propose new statistical methods for analyzing genetic case/control association data in which cases can be further classified into subtypes, for example, based on clinical features. The primary utility of our work is the ability to distinguish between subtype-specific and modifier effec...
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| 出版年: | Hum Hered |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
S. Karger AG
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7077092/ https://ncbi.nlm.nih.gov/pubmed/21849790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000327158 |
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