The conserved DNMT1-dependent methylation regions in human cells are vulnerable to neurotoxicant rotenone exposure

BACKGROUND: Allele-specific DNA methylation (ASM) describes genomic loci that maintain CpG methylation at only one inherited allele rather than having coordinated methylation across both alleles. The most prominent of these regions are germline ASMs (gASMs) that control the expression of imprinted g...

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Vydáno v:Epigenetics Chromatin
Hlavní autoři: Freeman, Dana M., Lou, Dan, Li, Yanqiang, Martos, Suzanne N., Wang, Zhibin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076959/
https://ncbi.nlm.nih.gov/pubmed/32178731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-020-00338-8
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