Exploring the Complexity of Processing-Induced Dehydration during Hot Melt Extrusion Using In-Line Raman Spectroscopy

The specific aim in this study was to understand the effect of critical process parameters on the solid form composition of model drug compounds during hot melt extrusion using in-line Raman spectroscopy combined with Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) modeling for sem...

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Detaylı Bibliyografya
Yayımlandı:Pharmaceutics
Asıl Yazarlar: Arnfast, Lærke, van Renterghem, Jeroen, Aho, Johanna, Bøtker, Johan, Raijada, Dhara, Baldursdóttir, Stefania, De Beer, Thomas, Rantanen, Jukka
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076463/
https://ncbi.nlm.nih.gov/pubmed/32024085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020116
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