Exploring the Complexity of Processing-Induced Dehydration during Hot Melt Extrusion Using In-Line Raman Spectroscopy

The specific aim in this study was to understand the effect of critical process parameters on the solid form composition of model drug compounds during hot melt extrusion using in-line Raman spectroscopy combined with Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) modeling for sem...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Arnfast, Lærke, van Renterghem, Jeroen, Aho, Johanna, Bøtker, Johan, Raijada, Dhara, Baldursdóttir, Stefania, De Beer, Thomas, Rantanen, Jukka
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076463/
https://ncbi.nlm.nih.gov/pubmed/32024085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020116
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge