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An F-Box Protein, Mdm30, Interacts with TREX Subunit Sub2 To Regulate Cellular Abundance Cotranscriptionally in Orchestrating mRNA Export Independently of Splicing and Mitochondrial Function

Although an F-box protein, Mdm30, is found to regulate ubiquitylation of the Sub2 component of TREX (transcription-export) complex for proteasomal degradation in stimulation of mRNA export, it remains unknown whether such ubiquitin-proteasome system (UPS) regulation of Sub2 occurs cotranscriptionall...

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Publicado en:Mol Cell Biol
Main Authors: Ferdoush, Jannatul, Sen, Rwik, Durairaj, Geetha, Barman, Priyanka, Kaja, Amala, Guha, Shalini, Bhaumik, Sukesh R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076257/
https://ncbi.nlm.nih.gov/pubmed/31932480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00570-19
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