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Fine-Tuning of FACT by the Ubiquitin Proteasome System in Regulation of Transcriptional Elongation

FACT (facilitates chromatin transcription), an evolutionarily conserved histone chaperone involved in transcription and other DNA transactions, is upregulated in cancers, and its downregulation is associated with cellular death. However, it is not clearly understood how FACT is fine-tuned for normal...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Sen, Rwik, Ferdoush, Jannatul, Kaja, Amala, Bhaumik, Sukesh R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959319/
https://ncbi.nlm.nih.gov/pubmed/27044865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01112-15
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