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Fine-Tuning of FACT by the Ubiquitin Proteasome System in Regulation of Transcriptional Elongation
FACT (facilitates chromatin transcription), an evolutionarily conserved histone chaperone involved in transcription and other DNA transactions, is upregulated in cancers, and its downregulation is associated with cellular death. However, it is not clearly understood how FACT is fine-tuned for normal...
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Publicado no: | Mol Cell Biol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959319/ https://ncbi.nlm.nih.gov/pubmed/27044865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01112-15 |
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