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Distinct Functions of the Cap-Binding Complex in Stimulation of Nuclear mRNA Export
Cap-binding complex (CBC) associates cotranscriptionally with the cap structure at the 5′ end of nascent mRNA to protect it from exonucleolytic degradation. Here, we show that CBC promotes the targeting of an mRNA export adaptor, Yra1 (forming transcription export [TREX] complex with THO and Sub2),...
Tallennettuna:
| Julkaisussa: | Mol Cell Biol |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Microbiology
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6447411/ https://ncbi.nlm.nih.gov/pubmed/30745412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00540-18 |
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