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Distinct Functions of the Cap-Binding Complex in Stimulation of Nuclear mRNA Export

Cap-binding complex (CBC) associates cotranscriptionally with the cap structure at the 5′ end of nascent mRNA to protect it from exonucleolytic degradation. Here, we show that CBC promotes the targeting of an mRNA export adaptor, Yra1 (forming transcription export [TREX] complex with THO and Sub2),...

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Pubblicato in:Mol Cell Biol
Autori principali: Sen, Rwik, Barman, Priyanka, Kaja, Amala, Ferdoush, Jannatul, Lahudkar, Shweta, Roy, Arpan, Bhaumik, Sukesh R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447411/
https://ncbi.nlm.nih.gov/pubmed/30745412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00540-18
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