Distinct Functions of the Cap-Binding Complex in Stimulation of Nuclear mRNA Export

Cap-binding complex (CBC) associates cotranscriptionally with the cap structure at the 5′ end of nascent mRNA to protect it from exonucleolytic degradation. Here, we show that CBC promotes the targeting of an mRNA export adaptor, Yra1 (forming transcription export [TREX] complex with THO and Sub2),...

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Udgivet i:Mol Cell Biol
Main Authors: Sen, Rwik, Barman, Priyanka, Kaja, Amala, Ferdoush, Jannatul, Lahudkar, Shweta, Roy, Arpan, Bhaumik, Sukesh R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447411/
https://ncbi.nlm.nih.gov/pubmed/30745412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00540-18
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