Histone Lysine Demethylases KDM5B and KDM5C Modulate Genome Activation and Stability in Porcine Embryos

The lysine demethylases KDM5B and KDM5C are highly, but transiently, expressed in porcine embryos around the genome activation stage. Attenuation of KDM5B and KDM5C mRNA hampered embryo development to the blastocyst stage in fertilized, parthenogenetically activated and nuclear transfer embryos. Whi...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Glanzner, Werner Giehl, Gutierrez, Karina, Rissi, Vitor Braga, de Macedo, Mariana Priotto, Lopez, Rosalba, Currin, Luke, Dicks, Naomi, Baldassarre, Hernan, Agellon, Luis B., Bordignon, Vilceu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076052/
https://ncbi.nlm.nih.gov/pubmed/32211412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00151
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