Tauroursodeoxycholic acid/TGR5 signaling promotes survival and early development of glucose-stressed porcine embryos

Conditions of impaired energy and nutrient homeostasis, such as diabetes and obesity, are associated with infertility. Hyperglycemia increases endoplasmic reticulum stress as well as oxidative stress and reduces embryo development and quality. Oxidative stress also causes deoxyribonucleic acid damag...

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Dades bibliogràfiques
Publicat a:Biol Reprod
Autors principals: Dicks, Naomi, Gutierrez, Karina, Currin, Luke, de Macedo, Mariana P, Glanzner, Werner G, Mondadori, Rafael G, Michalak, Marek, Agellon, Luis B, Bordignon, Vilceu
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256098/
https://ncbi.nlm.nih.gov/pubmed/33889948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioab072
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