Tauroursodeoxycholic acid/TGR5 signaling promotes survival and early development of glucose-stressed porcine embryos

Conditions of impaired energy and nutrient homeostasis, such as diabetes and obesity, are associated with infertility. Hyperglycemia increases endoplasmic reticulum stress as well as oxidative stress and reduces embryo development and quality. Oxidative stress also causes deoxyribonucleic acid damag...

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Bibliographic Details
Published in:Biol Reprod
Main Authors: Dicks, Naomi, Gutierrez, Karina, Currin, Luke, de Macedo, Mariana P, Glanzner, Werner G, Mondadori, Rafael G, Michalak, Marek, Agellon, Luis B, Bordignon, Vilceu
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256098/
https://ncbi.nlm.nih.gov/pubmed/33889948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioab072
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