Histone Lysine Demethylases KDM5B and KDM5C Modulate Genome Activation and Stability in Porcine Embryos

The lysine demethylases KDM5B and KDM5C are highly, but transiently, expressed in porcine embryos around the genome activation stage. Attenuation of KDM5B and KDM5C mRNA hampered embryo development to the blastocyst stage in fertilized, parthenogenetically activated and nuclear transfer embryos. Whi...

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Publicat a:Front Cell Dev Biol
Autors principals: Glanzner, Werner Giehl, Gutierrez, Karina, Rissi, Vitor Braga, de Macedo, Mariana Priotto, Lopez, Rosalba, Currin, Luke, Dicks, Naomi, Baldassarre, Hernan, Agellon, Luis B., Bordignon, Vilceu
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076052/
https://ncbi.nlm.nih.gov/pubmed/32211412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00151
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