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Analysis of L-arginine:glycine amidinotransferase-, creatine- and homoarginine-dependent gene regulation in the murine heart

L-arginine:glycine amidinotransferase (AGAT) and its metabolites creatine and homoarginine (HA) have been linked to cardiovascular pathologies in both human and murine studies, but the underlying molecular mechanisms are poorly understood. Here, we report the first analysis of heart transcriptome va...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Jensen, Märit, Müller, Christian, Choe, Chi-un, Schwedhelm, Edzard, Zeller, Tanja
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076046/
https://ncbi.nlm.nih.gov/pubmed/32179820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61638-3
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