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microRNA-670 modulates Igf2bp1 expression to regulate RNA methylation in parthenogenetic mouse embryonic development

Aberrant epigenetic modification, including N(6)-methylation of adenosine (m6A), has been frequently reported in embryos derived from parthenogenetic activation (PA). However, the role of Igf2bp1 expression pattern in m6A modification and the mechanism through which Igf2bp1 function is regulated in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hao, Jindong, Hu, Haobo, Jiang, Ziping, Yu, Xianfeng, Li, Chengshun, Chen, Lin, Xia, Yidan, Liu, Da, Wang, Dongxu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076016/
https://ncbi.nlm.nih.gov/pubmed/32179813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61816-3
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