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microRNA-670 modulates Igf2bp1 expression to regulate RNA methylation in parthenogenetic mouse embryonic development

Aberrant epigenetic modification, including N(6)-methylation of adenosine (m6A), has been frequently reported in embryos derived from parthenogenetic activation (PA). However, the role of Igf2bp1 expression pattern in m6A modification and the mechanism through which Igf2bp1 function is regulated in...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Hao, Jindong, Hu, Haobo, Jiang, Ziping, Yu, Xianfeng, Li, Chengshun, Chen, Lin, Xia, Yidan, Liu, Da, Wang, Dongxu
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076016/
https://ncbi.nlm.nih.gov/pubmed/32179813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61816-3
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