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MicroRNA-873 (MiRNA-873) Inhibits Glioblastoma Tumorigenesis and Metastasis by Suppressing the Expression of IGF2BP1

Glioblastoma multiforme (GBM) is known as a highly malignant brain tumor with a poor prognosis, despite intensive research and clinical efforts. In this study, we observed that microRNA-873 (miR-873) was expressed at low levels in GBM and that the overexpression of miR-873 dramatically reduced the c...

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Vydáno v:J Biol Chem
Hlavní autoři: Wang, Ren-jie, Li, Jian-wei, Bao, Bu-he, Wu, Huan-cheng, Du, Zhen-hua, Su, Jing-liang, Zhang, Ming-hua, Liang, Hai-qian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423684/
https://ncbi.nlm.nih.gov/pubmed/25670861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.624700
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