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Hypoxia-Inducible Factor (HIF)-2α Reprograms Liver Macrophages to Protect Against Acute Liver Injury via the Production of Interleukin-6
Acetaminophen (APAP) overdose represents the most frequent cause of acute liver failure, resulting in death or liver transplantation in more than one-third of patients in the United States. The effectiveness of the only antidote, N-acetylcysteine (NAC), declines rapidly after APAP ingestion, long be...
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| 出版年: | Hepatology |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7075728/ https://ncbi.nlm.nih.gov/pubmed/31529728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30954 |
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