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Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseases
Hypoxia-inducible factors (HIFs) are stabilized during adverse inflammatory processes associated with disorders such as inflammatory bowel disease, pathogen infection and acute lung injury, as well as during ischaemia–reperfusion injury. HIF stabilization and hypoxia-induced changes in gene expressi...
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| Publicado no: | Nat Rev Drug Discov |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4259899/ https://ncbi.nlm.nih.gov/pubmed/25359381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4422 |
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