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Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseases
Hypoxia-inducible factors (HIFs) are stabilized during adverse inflammatory processes associated with disorders such as inflammatory bowel disease, pathogen infection and acute lung injury, as well as during ischaemia–reperfusion injury. HIF stabilization and hypoxia-induced changes in gene expressi...
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| Publicado en: | Nat Rev Drug Discov |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4259899/ https://ncbi.nlm.nih.gov/pubmed/25359381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4422 |
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