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Inhibition of neutrophil elastase prevents neutrophil extracellular trap formation and rescues mice from endotoxic shock
Neutrophil elastase (NE) is a serine protease stored in the azurophilic granules of neutrophils and released into the extracellular milieu during inflammatory response or formation of neutrophil extracellular traps (NETs). Neutrophils release NETs to entrap pathogens by externalizing their cellular...
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| Publicado en: | Biomaterials |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7075277/ https://ncbi.nlm.nih.gov/pubmed/32045782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.119836 |
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