The histone methyltransferase Setd8 alters the chromatin landscape and regulates the expression of key transcription factors during erythroid differentiation

BACKGROUND: SETD8 is the sole methyltransferase capable of mono-methylating histone H4, lysine 20. SETD8 and H4K20me1 play a role in a number of essential biologic processes, including cell cycle progression, establishment of higher order chromatin structure, and transcriptional regulation. SETD8 is...

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Bibliografische gegevens
Gepubliceerd in:Epigenetics Chromatin
Hoofdauteurs: Myers, Jacquelyn A., Couch, Tyler, Murphy, Zachary, Malik, Jeffrey, Getman, Michael, Steiner, Laurie A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075014/
https://ncbi.nlm.nih.gov/pubmed/32178723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-020-00337-9
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