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The Methyltransferase Setd8 is Essential for Erythroblast Survival and Maturation

Erythropoiesis is a highly regulated process that generates enucleate red blood cells from committed erythroid progenitors. Chromatin condensation culminating in enucleation is a defining feature of this process. Setd8 is the sole enzyme that can mono-methylate histone H4, lysine 20 and is highly ex...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Malik, Jeffrey, Lillis, Jacquelyn A., Couch, Tyler, Getman, Michael, Steiner, Laurie A.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7748363/
https://ncbi.nlm.nih.gov/pubmed/29186677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.011
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