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Histone Methyltransferase Setd8 Represses Gata2 Expression and Regulates Erythroid Maturation

Setd8 is the sole histone methyltransferase in mammals capable of monomethylating histone H4 lysine 20 (H4K20me1). Setd8 is expressed at significantly higher levels in erythroid cells than any other cell or tissue type, suggesting that Setd8 has an erythroid-cell-specific function. To test this hypo...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Malik, Jeffrey, Getman, Michael, Steiner, Laurie A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438238/
https://ncbi.nlm.nih.gov/pubmed/25848090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01413-14
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