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Histone Methyltransferase Setd8 Represses Gata2 Expression and Regulates Erythroid Maturation

Setd8 is the sole histone methyltransferase in mammals capable of monomethylating histone H4 lysine 20 (H4K20me1). Setd8 is expressed at significantly higher levels in erythroid cells than any other cell or tissue type, suggesting that Setd8 has an erythroid-cell-specific function. To test this hypo...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Malik, Jeffrey, Getman, Michael, Steiner, Laurie A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438238/
https://ncbi.nlm.nih.gov/pubmed/25848090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01413-14
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