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Discovery of Two Brominated Oxindole Alkaloids as Staphylococcal DNA Gyrase and Pyruvate Kinase Inhibitors via Inverse Virtual Screening

In the present study, a small marine-derived natural products library was assessed for antibacterial potential. Among 36 isolated compounds, a number of bis-indole derivatives exhibited growth-inhibitory activity towards Gram-positive strains (Bacillus subtilis and multidrug-resistant Staphylococcus...

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Detalhes bibliográficos
Publicado no:Microorganisms
Main Authors: Sayed, Ahmed M., Alhadrami, Hani A., El-Hawary, Seham S., Mohammed, Rabab, Hassan, Hossam M., Rateb, Mostafa E., Abdelmohsen, Usama Ramadan, Bakeer, Walid
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074965/
https://ncbi.nlm.nih.gov/pubmed/32093370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms8020293
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