New Pim-1 Kinase Inhibitor From the Co-culture of Two Sponge-Associated Actinomycetes

Saccharomonospora sp. UR22 and Dietzia sp. UR66, two actinomycetes derived from the Red Sea sponge Callyspongia siphonella, were co-cultured and the induced metabolites were monitored by HPLC-DAD and TLC. Saccharomonosporine A (1), a novel brominated oxo-indole alkaloid, convolutamydine F (2) along...

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Dettagli Bibliografici
Pubblicato in:Front Chem
Autori principali: El-Hawary, Seham S., Sayed, Ahmed M., Mohammed, Rabab, Khanfar, Mohammad A., Rateb, Mostafa E., Mohammed, Tarek A., Hajjar, Dina, Hassan, Hossam M., Gulder, Tobias A. M., Abdelmohsen, Usama Ramadan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262321/
https://ncbi.nlm.nih.gov/pubmed/30525020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00538
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