Bioactive Brominated Oxindole Alkaloids from the Red Sea Sponge Callyspongia siphonella

In the present study, LC-HRESIMS-assisted dereplication along with bioactivity-guided isolation led to targeting two brominated oxindole alkaloids (compounds 1 and 2) which probably play a key role in the previously reported antibacterial, antibiofilm, and cytotoxicity of Callyspongia siphonella cru...

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發表在:Mar Drugs
Main Authors: El-Hawary, Seham S., Sayed, Ahmed M., Mohammed, Rabab, Hassan, Hossam M., Rateb, Mostafa E., Amin, Elham, Mohammed, Tarek A., El-Mesery, Mohamed, Bin Muhsinah, Abdullatif, Alsayari, Abdulrhman, Wajant, Harald, Anany, Mohamed A., Abdelmohsen, Usama Ramadan
格式: Artigo
語言:Inglês
出版: MDPI 2019
主題:
Communication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723499/
https://ncbi.nlm.nih.gov/pubmed/31395834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17080465
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