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PKCδ-dependent p47phox activation mediates methamphetamine-induced dopaminergic neurotoxicity

Protein kinase C (PKC) has been recognized to activate NADPH oxidase (PHOX). However, the interaction between PKC and PHOX in vivo remains elusive. Treatment with methamphetamine (MA) resulted in a selective increase in PKCδ expression out of PKC isoforms. PKCδ co-immunoprecipitated with p47phox, an...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Dang, Duy-Khanh, Shin, Eun-Joo, Kim, Dae-Joong, Tran, Hai-Quyen, Jeong, Ji Hoon, Jang, Choon-Gon, Ottersen, Ole Petter, Nah, Seung-Yeol, Hong, Jau-Shyong, Nabeshima, Toshitaka, Kim, Hyoung-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074955/
https://ncbi.nlm.nih.gov/pubmed/29269308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.12.018
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