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RECQ5: A Mysterious Helicase at the Interface of DNA Replication and Transcription

RECQ5 belongs to the RecQ family of DNA helicases. It is conserved from Drosophila to humans and its deficiency results in genomic instability and cancer susceptibility in mice. Human RECQ5 is known for its ability to regulate homologous recombination by disrupting RAD51 nucleoprotein filaments. It...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Andrs, Martin, Hasanova, Zdenka, Oravetzova, Anna, Dobrovolna, Jana, Janscak, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073763/
https://ncbi.nlm.nih.gov/pubmed/32098287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11020232
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