RECQ5: A Mysterious Helicase at the Interface of DNA Replication and Transcription

RECQ5 belongs to the RecQ family of DNA helicases. It is conserved from Drosophila to humans and its deficiency results in genomic instability and cancer susceptibility in mice. Human RECQ5 is known for its ability to regulate homologous recombination by disrupting RAD51 nucleoprotein filaments. It...

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Bibliographic Details
Published in:Genes (Basel)
Main Authors: Andrs, Martin, Hasanova, Zdenka, Oravetzova, Anna, Dobrovolna, Jana, Janscak, Pavel
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073763/
https://ncbi.nlm.nih.gov/pubmed/32098287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11020232
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