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RECQ5: A Mysterious Helicase at the Interface of DNA Replication and Transcription
RECQ5 belongs to the RecQ family of DNA helicases. It is conserved from Drosophila to humans and its deficiency results in genomic instability and cancer susceptibility in mice. Human RECQ5 is known for its ability to regulate homologous recombination by disrupting RAD51 nucleoprotein filaments. It...
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| Veröffentlicht in: | Genes (Basel) |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7073763/ https://ncbi.nlm.nih.gov/pubmed/32098287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11020232 |
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