Aloe-Emodin Induces Breast Tumor Cell Apoptosis through Upregulation of miR-15a/miR-16-1 That Suppresses BCL2

PURPOSE: Aloe-emodin (AE) is a natural compound derived from aloe vera and palmatum rhubarb and shows anticancer activities in various cancers. Bcl-2 family is the main regulator of cell death or cell survival. This study describes the effects of AE on proliferation of breast tumor (BT) cells. METHO...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Jiang, Xuefeng, Liu, Yusheng, Zhang, Guijuan, Lin, Shujun, Wu, Jieyan, Yan, Xianxin, Ma, Yi, Ma, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073502/
https://ncbi.nlm.nih.gov/pubmed/32190086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5108298
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