Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation

DNA methyltransferases (DNMTs) play a relevant role in epigenetic control of cancer cell survival and proliferation. Since only two DNMT inhibitors (azacitidine and decitabine) have been approved to date for the treatment of hematological malignancies, the development of novel potent and specific in...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Zwergel, Clemens, Fioravanti, Rossella, Stazi, Giulia, Sarno, Federica, Battistelli, Cecilia, Romanelli, Annalisa, Nebbioso, Angela, Mendes, Eduarda, Paulo, Alexandra, Strippoli, Raffaele, Tripodi, Marco, Pechalrieu, Dany, Arimondo, Paola B., De Luca, Teresa, Del Bufalo, Donatella, Trisciuoglio, Daniela, Altucci, Lucia, Valente, Sergio, Mai, Antonello
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073229/
https://ncbi.nlm.nih.gov/pubmed/32075099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020447
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker