Using Transcriptomic Analysis to Assess Double-Strand Break Repair Activity: Towards Precise in Vivo Genome Editing

Mutations in more than 200 retina-specific genes have been associated with inherited retinal diseases. Genome editing represents a promising emerging field in the treatment of monogenic disorders, as it aims to correct disease-causing mutations within the genome. Genome editing relies on highly spec...

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Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Pasquini, Giovanni, Cora, Virginia, Swiersy, Anka, Achberger, Kevin, Antkowiak, Lena, Müller, Brigitte, Wimmer, Tobias, Fraschka, Sabine Anne-Kristin, Casadei, Nicolas, Ueffing, Marius, Liebau, Stefan, Stieger, Knut, Busskamp, Volker
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073035/
https://ncbi.nlm.nih.gov/pubmed/32085662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041380
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