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The Pattern of AQP4 Expression in the Ageing Human Brain and in Cerebral Amyloid Angiopathy
In the absence of lymphatics, fluid and solutes such as amyloid-β (Aβ) are eliminated from the brain along basement membranes in the walls of cerebral capillaries and arteries—the Intramural Peri-Arterial Drainage (IPAD) pathway. IPAD fails with age and insoluble Aβ is deposited as plaques in the br...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7072949/ https://ncbi.nlm.nih.gov/pubmed/32059400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041225 |
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