The Pattern of AQP4 Expression in the Ageing Human Brain and in Cerebral Amyloid Angiopathy

In the absence of lymphatics, fluid and solutes such as amyloid-β (Aβ) are eliminated from the brain along basement membranes in the walls of cerebral capillaries and arteries—the Intramural Peri-Arterial Drainage (IPAD) pathway. IPAD fails with age and insoluble Aβ is deposited as plaques in the br...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Owasil, Raisah, O’Neill, Ronan, Keable, Abby, Nimmo, Jacqui, MacGregor Sharp, Matthew, Kelly, Louise, Saito, Satoshi, Simpson, Julie E., Weller, Roy O., Smith, Colin, Attems, Johannes, Wharton, Stephen B., Yuen, Ho Ming, Carare, Roxana O.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072949/
https://ncbi.nlm.nih.gov/pubmed/32059400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041225
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