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Microtubule-Mediated NLRP3 Inflammasome Activation Is Independent of Microtubule-Associated Innate Immune Factor GEF-H1 in Murine Macrophages

Inflammasomes are intracellular multiple protein complexes that mount innate immune responses to tissue damage and invading pathogens. Their excessive activation is crucial in the development and pathogenesis of inflammatory disorders. Microtubules have been reported to provide the platform for medi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lai, Hsuan-Ju, Hsu, Yi-Hsuan, Lee, Guan-Ying, Chiang, Hao-Sen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072875/
https://ncbi.nlm.nih.gov/pubmed/32075101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041302
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