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The Microtubule-Associated Innate Immune Sensor GEF-H1 Does Not Influence Mouse Norovirus Replication in Murine Macrophages

Norovirus is an acute infection of the gastrointestinal tract causing rapid induction of vomiting and diarrhoea. The infection is sensed and controlled by the innate immune system, particularly by the RNA helicase MDA-5 and type I and III interferons (IFNs). We have observed that intracellular repli...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Fritzlar, Svenja, White, Peter A., Mackenzie, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356845/
https://ncbi.nlm.nih.gov/pubmed/30634661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11010047
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