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The IGF-II–Insulin Receptor Isoform-A Autocrine Signal in Cancer: Actionable Perspectives
Insulin receptor overexpression is a common event in human cancer. Its overexpression is associated with a relative increase in the expression of its isoform A (IR(A)), a shorter variant lacking 11 aa in the extracellular domain, conferring high affinity for the binding of IGF-II along with added in...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7072655/ https://ncbi.nlm.nih.gov/pubmed/32033443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020366 |
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