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Isoform- and Paralog-Switching in IR-Signaling: When Diabetes Opens the Gates to Cancer
Insulin receptor (IR) and IR-related signaling defects have been shown to trigger insulin-resistance in insulin-dependent cells and ultimately to give rise to type 2 diabetes in mammalian organisms. IR expression is ubiquitous in mammalian tissues, and its over-expression is also a common finding in...
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| Publicat a: | Biomolecules |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7761347/ https://ncbi.nlm.nih.gov/pubmed/33266015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10121617 |
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