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Dynamic Changes in Function and Proteomic Composition of Extracellular Vesicles from Hepatic Stellate Cells during Cellular Activation

During chronic liver injury, hepatic stellate cells (HSC) undergo activation and are the principal cellular source of collagenous scar. In this study, we found that activation of mouse HSC (mHSC) was associated with a 4.5-fold increase in extracellular vesicle (EV) production and that fibrogenic gen...

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Vydáno v:Cells
Hlavní autoři: Li, Xinlei, Chen, Ruju, Kemper, Sherri, Brigstock, David R
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072607/
https://ncbi.nlm.nih.gov/pubmed/31991791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020290
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