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Dynamic Changes in Function and Proteomic Composition of Extracellular Vesicles from Hepatic Stellate Cells during Cellular Activation

During chronic liver injury, hepatic stellate cells (HSC) undergo activation and are the principal cellular source of collagenous scar. In this study, we found that activation of mouse HSC (mHSC) was associated with a 4.5-fold increase in extracellular vesicle (EV) production and that fibrogenic gen...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Li, Xinlei, Chen, Ruju, Kemper, Sherri, Brigstock, David R
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072607/
https://ncbi.nlm.nih.gov/pubmed/31991791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020290
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