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Dynamic Changes in Function and Proteomic Composition of Extracellular Vesicles from Hepatic Stellate Cells during Cellular Activation

During chronic liver injury, hepatic stellate cells (HSC) undergo activation and are the principal cellular source of collagenous scar. In this study, we found that activation of mouse HSC (mHSC) was associated with a 4.5-fold increase in extracellular vesicle (EV) production and that fibrogenic gen...

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書誌詳細
出版年:Cells
主要な著者: Li, Xinlei, Chen, Ruju, Kemper, Sherri, Brigstock, David R
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072607/
https://ncbi.nlm.nih.gov/pubmed/31991791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020290
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