A-Kinase Anchoring Proteins Diminish TGF-β(1)/Cigarette Smoke-Induced Epithelial-To-Mesenchymal Transition

Epithelial-to-mesenchymal transition (EMT) plays a role in chronic obstructive pulmonary diseases (COPD). Cyclic adenosine monophosphate (cAMP) can inhibit transforming growth factor-β1 (TGF-β1) mediated EMT. Although compartmentalization via A-kinase anchoring proteins (AKAPs) is central to cAMP si...

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Udgivet i:Cells
Main Authors: Zuo, Haoxiao, Trombetta-Lima, Marina, Heijink, Irene H., van der Veen, Christina H. T. J., Hesse, Laura, Faber, Klaas Nico, Poppinga, Wilfred J., Maarsingh, Harm, Nikolaev, Viacheslav O., Schmidt, Martina
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072527/
https://ncbi.nlm.nih.gov/pubmed/32028718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020356
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