Glycochenodeoxycholate Promotes Liver Fibrosis in Mice with Hepatocellular Cholestasis

Hydrophobic bile salts are considered to promote liver fibrosis in cholestasis. However, evidence for this widely accepted hypothesis remains scarce. In established animal models of cholestasis, e.g., by Mdr2 knockout, cholestasis and fibrosis are both secondary to biliary damage. Therefore, to test...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cells
Hlavní autoři: Hohenester, Simon, Kanitz, Veronika, Kremer, Andreas E., Paulusma, Coen C., Wimmer, Ralf, Kuehn, Helen, Denk, Gerald, Horst, David, Oude Elferink, Ronald, Beuers, Ulrich
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072501/
https://ncbi.nlm.nih.gov/pubmed/31979271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020281
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky