TDP1 and TOP1 Modulation in Olaparib-Resistant Cancer Determines the Efficacy of Subsequent Chemotherapy

The aim of this study was to elucidate the carryover effect of olaparib to subsequent chemotherapy and its underlying mechanisms. We generated olaparib-resistant SNU-484, SNU-601, SNU-668, and KATO-III gastric cancer cell lines and confirmed their resistance by cell viability and colony forming assa...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Kim, Jin Won, Min, Ahrum, Im, Seock-Ah, Jang, Hyemin, Kim, Yu Jin, Kim, Hee-Jun, Lee, Kyung-Hun, Kim, Tae-Yong, Lee, Keun Wook, Oh, Do-Youn, Kim, Jee-Hyun, Bang, Yung-Jue
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072281/
https://ncbi.nlm.nih.gov/pubmed/32028591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020334
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