Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma

Multiple myeloma (MM) is the second most common hematological cancer and is characterized by genetic features including translocations, chromosomal copy number aberrations, and mutations in key oncogene and tumor suppressor genes. Dysregulation of the tumor suppressor TP53 is important in the pathog...

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Detalles Bibliográficos
Publicado en:Cells
Autores principales: Flynt, Erin, Bisht, Kamlesh, Sridharan, Vinidhra, Ortiz, María, Towfic, Fadi, Thakurta, Anjan
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072230/
https://ncbi.nlm.nih.gov/pubmed/31991614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020287
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