High subclonal fraction of 17p deletion is associated with poor prognosis in multiple myeloma

Deletions of chromosome 17p (del17p) that span the TP53 gene are associated with poor outcome in multiple myeloma (MM), but the prognostic value of del17p cancer clonal fraction (CCF) remains unclear. We applied uniform cytogenetic assessments in a large cohort of newly diagnosed MM (NDMM) patients...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Blood
Κύριοι συγγραφείς: Thakurta, Anjan, Ortiz, Maria, Blecua, Pedro, Towfic, Fadi, Corre, Jill, Serbina, Natalya V., Flynt, Erin, Yu, Zhinuan, Yang, Zhihong, Palumbo, Antonio, Dimopoulos, Meletios A., Gutierrez, Norma C., Goldschmidt, Hartmut, Sonneveld, Pieter, Avet-Loiseau, Herve
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2019
Θέματα:
Lymphoid Neoplasia
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428662/
https://ncbi.nlm.nih.gov/pubmed/30692124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-10-880831
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