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Megalin: a Novel Determinant of Renin-Angiotensin System Activity in the Kidney?

PURPOSE OF REVIEW: Megalin is well known for its role in the reabsorption of proteins from the ultrafiltrate. Recent studies suggest that megalin also reabsorbs renin and angiotensinogen. Indeed, without megalin urinary renin and angiotensinogen levels massively increase, and even prorenin becomes d...

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Vydáno v:Curr Hypertens Rep
Hlavní autoři: Sun, Yuan, Lu, Xifeng, Danser, A. H. Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072043/
https://ncbi.nlm.nih.gov/pubmed/32172431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11906-020-01037-1
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