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Megalin: a Novel Determinant of Renin-Angiotensin System Activity in the Kidney?

PURPOSE OF REVIEW: Megalin is well known for its role in the reabsorption of proteins from the ultrafiltrate. Recent studies suggest that megalin also reabsorbs renin and angiotensinogen. Indeed, without megalin urinary renin and angiotensinogen levels massively increase, and even prorenin becomes d...

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Bibliographic Details
Published in:Curr Hypertens Rep
Main Authors: Sun, Yuan, Lu, Xifeng, Danser, A. H. Jan
Format: Artigo
Language:Inglês
Published: Springer US 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072043/
https://ncbi.nlm.nih.gov/pubmed/32172431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11906-020-01037-1
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