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Megalin: a Novel Determinant of Renin-Angiotensin System Activity in the Kidney?

PURPOSE OF REVIEW: Megalin is well known for its role in the reabsorption of proteins from the ultrafiltrate. Recent studies suggest that megalin also reabsorbs renin and angiotensinogen. Indeed, without megalin urinary renin and angiotensinogen levels massively increase, and even prorenin becomes d...

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Publicado en:Curr Hypertens Rep
Autores principales: Sun, Yuan, Lu, Xifeng, Danser, A. H. Jan
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072043/
https://ncbi.nlm.nih.gov/pubmed/32172431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11906-020-01037-1
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