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Megalin: a Novel Determinant of Renin-Angiotensin System Activity in the Kidney?

PURPOSE OF REVIEW: Megalin is well known for its role in the reabsorption of proteins from the ultrafiltrate. Recent studies suggest that megalin also reabsorbs renin and angiotensinogen. Indeed, without megalin urinary renin and angiotensinogen levels massively increase, and even prorenin becomes d...

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Bibliografski detalji
Izdano u:Curr Hypertens Rep
Glavni autori: Sun, Yuan, Lu, Xifeng, Danser, A. H. Jan
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072043/
https://ncbi.nlm.nih.gov/pubmed/32172431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11906-020-01037-1
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