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Megalin: a Novel Determinant of Renin-Angiotensin System Activity in the Kidney?

PURPOSE OF REVIEW: Megalin is well known for its role in the reabsorption of proteins from the ultrafiltrate. Recent studies suggest that megalin also reabsorbs renin and angiotensinogen. Indeed, without megalin urinary renin and angiotensinogen levels massively increase, and even prorenin becomes d...

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Détails bibliographiques
Publié dans:Curr Hypertens Rep
Auteurs principaux: Sun, Yuan, Lu, Xifeng, Danser, A. H. Jan
Format: Artigo
Langue:Inglês
Publié: Springer US 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072043/
https://ncbi.nlm.nih.gov/pubmed/32172431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11906-020-01037-1
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