High levels of genetically-intact HIV in HLA-DR+ memory T-cells indicates their value for reservoir studies

OBJECTIVE: The contribution of HLA-DR+ memory CD4+ T-cells to the HIV reservoir during prolonged antiretroviral therapy is unclear as these cells are commonly excluded when assessing for replication-competent HIV. To address this issue, we examined the distribution of genetically intact HIV DNA with...

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Publicat a:AIDS
Autors principals: HORSBURGH, Bethany A., LEE, Eunok, HIENER, Bonnie, EDEN, John-Sebastian, SCHLUB, Timothy E., VON STOCKENSTROM, Susanne, ODEVALL, Lina, MILUSH, Jeffrey M., LIEGLER, Teri, SINCLAIR, Elizabeth, HOH, Rebecca, BORITZ, Eli A., DOUEK, Daniel C., FROMENTIN, Remi, CHOMONT, Nicolas, DEEKS, Steven G., HECHT, Frederick M., PALMER, Sarah
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071960/
https://ncbi.nlm.nih.gov/pubmed/31913161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002465
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